Splintless Virtual Surgical Plan with Mandible-first Technique: 3D Accuracy Analysis

Inclusion Criteria: * Men and women * Age over 18 and under 60 * Diagnosis of dento-skeletal dysmorphosis involving the middle third and lower part of the face * Patients with consent to surgery * Patients in good general health according to the evaluation of the PI and on the basis of the anamnesis and clinical examination Exclusion Criteria: * History of previous maxillomandibular fracture * Treatment with anticoagulant drugs * Treatment with intravenous bisphosphonates * Treatment with anticonvulsants * Patient's inability to maintain home hygiene standards in accordance with the study requirements * History of drug and/or alcohol abuse * Chronic corticosteroid therapy * Radiotherapy, chemotherapy and/or immunosuppressive treatment or radiotherapy in the last 5 years * Psychosis * Pregnant or breastfeeding * Poor compliance * Endocrinological disorders in poor pharmacological control * Other uncontrolled systemic conditions that preclude performing surgical procedures