PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome (NCT06903026) | Clinical Trial Compass
RecruitingNot Applicable
PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome
France250 participantsStarted 2023-03-17
Plain-language summary
Amnesic stroke is an amnestic syndrome lasting less than 24 hours characterized by the occurrence of anterograde amnesia often associated with retrograde amnesia, the pathophysiology of which is still poorly understood at present. A recent study on a small sample size (N=29) highlighted an association between obstructive sleep apnea syndrome and amnesic stroke. Our study seeks to confirm or refute these results on a larger cohort (N=200-250). A better understanding of the pathophysiological processes involved would open up new therapeutic avenues.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult patients seen for consultation in the Neuropsychology Department of Strasbourg University Hospital between March 1, 2015 and December 31, 2021 following an episode of amnestic stroke meeting the Hodges and Warlow criteria:
* The stroke must have been documented and reported by a competent witness present during the stroke.
* Anterograde amnesia during the stroke.
* Absence of vigilance, personality, and cognitive disorders other than memory disorders (aphasia, apraxia, etc.).
* Absence of focal neurological symptoms during the episode and its aftermath.
* Absence of epileptic manifestations.
* Resolution of the episode in less than 24 hours.
* Exclusion of patients with a history of recent head trauma or active epilepsy (undergoing regular treatment or having experienced a seizure in the last 2 years).
* Subjects who have not expressed opposition to the reuse of their data for scientific research purposes.
Exclusion Criteria:
* Patients who have expressed opposition to the retrospective reuse of their data for scientific research purposes.
* Patients with active epilepsy
* Patients with recent head trauma
* Patients with an MMS \< or equal to 25
* Subject under guardianship or curatorship
* Subject under judicial protection
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To assess the prevalence of obstructive sleep apnea syndrome in patients who have experienced an amnestic stroke.