Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically … (NCT06901544) | Clinical Trial Compass
CompletedNot Applicable
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
Egypt100 participantsStarted 2025-03-04
Plain-language summary
In this study the investigators going to evaluate the "CLI" as an early prognostic indicator for post-operative abdominal sepsis in critically ill patients.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age: ≥18 years old presented with Post-operative intra-abdominal sepsis due to secondary peritonitis.
* Sex: Both sexes.
* Post-Operative secondary peritonitis eg. Perforated viscus and abdominal abscess.
* Estimated length of ICU stays ≥48 hrs.
Exclusion Criteria:
* Patient refusal.
* Advanced Liver diseases According New MELD score ≥ 20 )Kamath et al.,2001)
* Renal diseases (Moderate decrease in GFR 30-59 ml/min/1.73m²--Severe decrease in GFR 15-29 ml/min/1.73m²--Kidney failure less than 15 ml/min/1.73m² or on Hemodialysis).
* Pregnancy.
* Primary peritonitis.
* Tertiary peritonitis.
* Mortality within first 48hrs of ICU admission.
* Advanced malignancy ( Stage III localized malignancy with spreading lymph nodes Stage IV spreading to Other parts of the body such as to the liver, lungs and bones).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial tracked a measurement called the 'Capillary Leak Index' in patients who had surgery for conditions like a perforated organ or a severe abdominal infection — is this something that was or could be measured in my case, and what does it tell us about my risk?
2Since this study looked at whether patients with post-operative abdominal sepsis survived to 28 days, does my situation put me at risk for that kind of serious complication, and how would you monitor me for it?
3This trial has already been completed — does that mean there are findings or results I should know about that might influence how my care team approaches my treatment or recovery monitoring?
4For conditions like the ones studied here — appendicitis, bowel obstruction, or a perforated organ — are there specific warning signs of sepsis after surgery that I or my family should watch for at home?
5Based on what this study was measuring, would tracking something like a capillary leak index be a standard part of my post-operative monitoring, or is that only done in a research setting?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.