The Efficacy of Salvia Officinalis Gel in the Treatment of Periodontitis CLINICAL TRIAL

Inclusion Criteria: * patients diagnosed with periodontitis had at least 20 natural teeth, with probing pocket depth (PPD) ≥ 5 mm and attachment loss ≥ 4 mm Exclusion Criteria: * Exclusion criteria were pregnancy, lactation, smoking, and any systemic disease that might affect periodontal disease progression or require antibiotic usage. Likewise, patients who had received anti-inflammatory medications or antibiotics in the preceding three months were excluded.