The goal of this observational study is to explore brain network changes and identify patterns related to hyperphagia, hormonal treatment effects, and cognitive deficits in adults with Prader-Willi Syndrome (PWS). The main questions it aims to answer are: * How are brain connectivity patterns altered in PWS patients compared to healthy and obese controls? * How do brain network changes relate to hyperphagia and the response to growth hormone therapy? Researchers will compare PWS patients to healthy and obese controls to see if there are significant differences in brain network connectivity before and after meals and growth hormone therapy. Ultimately, researchers will try to develop predictive models of treatment outcomes using AI and machine learning.
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Functional connectivity patterns
Timeframe: Before and after the intervention (immediately after the end of the intervention for hunger, up to a year for GH).