CompletedNot Applicable

Does Botulinum Toxin Type-A Injection an Effective Way of Relieving Pain in Myofascial Pain Syndrome Patients or Not

38 participantsStarted 2009-08-26

Plain-language summary

In this research prilocaine and botulinum toxin (BoNT-A) interventions prospectively compared to find out the effect of BoNT-A injection on myofascial pain syndrome (MPS). The main question it aims to answer is: Does Botulinum Toxin Type-A an Effective Way of Relieving Pain in Myofascial Pain Syndrome or not? For this purpose thirty-eight patients randomly assigned into two study groups. While BoNT-A injection group (BIG group n=19) treated with 20 units of toxin to each trigger point (TP), remaining treated with 2 ml prilocaine (PIG group n=19) with same procedure. Pre-treatment, 2nd and 6th weeks findings were clinically recorded.

Who can participate

Age range

20 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Age ≥ 20 years Presence of myofascial pain syndrome (MPS) symptoms for more than 3 months Ability and willingness to provide written informed consent Exclusion Criteria: Any injection to trigger points within the last 2 months Diagnosis of fibromyalgia syndrome Presence of significant respiratory or cardiovascular disease Presence of psychiatric disorders that may interfere with study participation History of shoulder or cervical spine intervention within the last year Presence of cervical myelopathy or cervical radiculopathy Inability to cooperate with study procedures or assessments

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Visual analog scale, 4-point verbal rating scale, Pressure pain threshold

Timeframe: Pre-treatment, 2nd and 6th week scores were recorded.

Trial details

NCT IDNCT06899438

SponsorBursa City Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2010-01-26

View on ClinicalTrials.gov More Myofacial Pain Syndromes trials