Active — Not RecruitingNot Applicable

Omega-3 Supplementation for Pediatric Migraine

United States58 participantsStarted 2025-04-17

Plain-language summary

The purpose of the study is to assess the biochemical and clinical effects of omega-3 polyunsaturated fatty acid (PUFA) supplementation in youth suffering from migraine, including its effects on migraine disability, psychological distress, and overall quality of life. This study duration 12 weeks.

Who can participate

Age range10 Years – 17 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Males and females between the ages of 10 and 17 years * Parent consent and subject assent * Diagnosis of migraine based on the third edition of the International Classification of Headache Disorders (ICHD-3) criteria Exclusion Criteria: * Known allergy to fish or seafood * Current use of an omega-3 dietary supplement * Significant neurological or psychiatric disorders or developmental delays * Non-English speaking * Allergy to coconut * Pregnancy

What they're measuring

Change in Omega-3 index levels in blood

Timeframe: Baseline and 12 weeks

Trial details

NCT IDNCT06899074

SponsorUniversity of North Carolina, Chapel Hill

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03

View on ClinicalTrials.gov More Migraine trials