Active — Not RecruitingNot Applicable

Ventilator Settings and Outcomes in Pediatric Patients on ECMO for Severe Respiratory Failure

Netherlands750 participantsStarted 2024-09-01

Plain-language summary

This study aims to describe the effects of ECMO initiation on the intensity of ventilation in the first 24 hours after ECMO initiation and to explore associations between changes in ventilation intensity and hospital mortality in critically ill pediatric patients requiring ECMO for respiratory failure, using the 'Extracorporeal Life Support Organization' (ELSO) registry.

Who can participate

Age range29 Days – 18 Years

SexALL

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Inclusion criteria

✓. Patients (aged ≥29 days to ≤18 years) receiving ECMO between January 1, 2012, and December 31, 2022, in an ELSO affiliated center; and
✓. Requiring ECMO for a pulmonary indication.

Exclusion criteria

✕. Patients with missing ventilatory variables required to assess ventilation intensity;
✕. patients who were lost to follow up with respect to hospital mortality.

What they're measuring

Hospital mortality

Timeframe: Up to 90 days of study or whatever comes first

Trial details

NCT IDNCT06899009

SponsorUniversity Medical Center Groningen

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-03-01

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