Cortisol and Obesity - A Vicious Cycle? Hypoglycemia After Bariatric Surgery - Association With C… (NCT06896682) | Clinical Trial Compass
RecruitingNot Applicable
Cortisol and Obesity - A Vicious Cycle? Hypoglycemia After Bariatric Surgery - Association With Cortisol Metabolism?
Denmark100 participantsStarted 2025-07-08
Plain-language summary
The goal of this observational study is to learn about how bariatric surgery affects the metabolism of cortisol.
The main question it aims to answer is whether changes in cortisol contribute to the development of reactive hypoglycemia?
100 individuals who have previously undergone bariatric surgery, are planned to be included.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Participants must have undergone one of the following bariatric procedures at least 12 months prior:
* Roux-en-Y gastric bypass
* Gastric sleeve
Exclusion Criteria
* Pregnancy and breastfeeding
* Nephrotic syndrome (kidney disease with protein loss in urine), liver cirrhosis, or severe malnutrition, as these conditions reduce cortisol-binding globulin (CBG) levels, affecting total cortisol concentration
* Use of corticosteroid medications, such as prednisolone
* Use of opiod-containing medication
* Use of medications containing estrogen, such as hormone therapy for menopause
* Known adrenal disease affecting cortisol metabolism, including autonomous cortisol production and Cushing's syndrome
* Diabetes that does not require medical treatment
* Previously diagnosed reactive hypoglycemia after bariatric surgery requiring medical treatment
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.