Not Yet RecruitingNot Applicable

Effect of Nano Hydroxy Apatite Varnish and Potassium Nitrate Gel on the MIH-affected Permanent Teeth

48 participantsStarted 2025-06-01

Plain-language summary

This clinical study main goal is to investigate the effectiveness of nano hydroxy apatite crystal varnish and potassium nitrate gel as a non invasive approach in managing MIH-affected teeth.

Who can participate

Age range6 Years – 10 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Children aged from six to ten years old.
✓. Medically free children according to the history taken from their parents.
✓. Children who are categorized as Class I or II according to the American Society of Anaesthesiologists (ASA).
✓. Children whom their parents accept to comply with the follow-up visits.
✓. Children who accept, and their guardians, to participate in the study by signing the informed consent.
✓. Children with no more than four cavitated primary teeth.
✓. MIH-affected permanent teeth, suffering from dentin hypersensitivity, (MIH-TNI 3, 4a).
✓. Positive Schiff Cold Airblasting Sensitivity score (score 1, 2, or 3).

Exclusion criteria

✕. Children with severe behavioral or emotional disabilities.
✕. Children who received analgesics within the last 24 hours before the procedure.15
✕. Patients who are using chlorhexidine-based gels or mouthwashes.
✕. A tooth with signs and symptoms of irreversible pulpitis.
✕. A tooth with signs and symptoms of necrotic pulp.
✕. Sealing therapy or application of desensitizing agent on the MIH teeth within one month before participation in the study.
✕. Presence of dental caries on the MIH-affected permanent tooth.
✕. Presence of restoration(s) on MIH-affected permanent tooth.

What they're measuring

Dentin Hypersensitivity

Timeframe: Baseline, 15 miutes pot-op, 2 weeks post-op, and 4 weeks post op.

Dentin Hypersensitivity

Timeframe: Baseline, 15 miutes pot-op, 2 weeks post-op, and 4 weeks post op.

Trial details

NCT IDNCT06896565

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-20

Contact for this trial

Mennat Allah AA Abd Elsabour, PhD student

+201026022605 mennatallah.ashraf@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Molar Incisor Hypomineralisation trials