Not Yet RecruitingNot Applicable

Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis

60 participantsStarted 2025-11

Plain-language summary

1. To evaluate the immunohistochemical expression of USP35 in cases of juvenile autoimmune hepatitis and control cases. 2. To correlate this with the level of necro-inflammation and extent of fibrosis using Massion's trichrome stain in cases of juvenile autoimmune hepatitis.

Who can participate

Age range1 Day – 18 Years

SexALL

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Exclusion criteria

✕. Cases with inadequate tissue in the paraffin block
✕. Children with viral hepatitis
✕. patients above the age of 18 years old

What they're measuring

Expression of USP35 in cases of juvenile autoimmune hepatitis

Timeframe: baseline

Trial details

NCT IDNCT06896383

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-11

Contact for this trial

Mariam Mohamed Rashwan, bachelor's degree

+20 1158056572 Mariam.rashwan@aun.edu.eg

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