RecruitingNot Applicable

An Observational Study for Gastric Cancer in Carriers of High Risk Helicobacter Pylori

China3,000 participantsStarted 2025-07-01

Plain-language summary

This study is intended to be a prospective observational cohort study. The incidence of gastric cancer and progression of gastric precancerous lesions will be compared between groups through prospective follow-up of a population with baseline negative gastric endoscopy, harboring high-risk Hp SNP subtypes and non-high-risk subtypes.

Who can participate

Age range40 Years

SexALL

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Inclusion criteria

✓. Age ≥ 40 years, gender is not limited.
✓. Able and willing to provide informed consent and willing to undergo baseline and follow-up examinations.

Exclusion criteria

✕. A history of diagnosed gastric cancer or other malignant tumors of the digestive tract.
✕. Comorbid severe underlying conditions (e.g., severe cardiopulmonary insufficiency, liver or renal failure, etc.) that are likely to result in a short life expectancy or render long-term follow-up impractical.
✕. Severe mental illness or incapacity to participate in the study due to lack of civil behavior.
✕. Pregnant or breastfeeding women.
✕. Other conditions that the investigator deems inappropriate for participation in the study.

What they're measuring

Difference in incidence of gastric cancer between the three groups (HP positive high-risk, HP positive non-high-risk, and HP negative) during a 3-year follow-up.

Timeframe: From enrollment to the end of the study in 3 years

Trial details

NCT IDNCT06896370

SponsorFudan University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2035-05-01

Contact for this trial

Dazhi Xu, PhD

86-18121299796 xudzh@fudan.edu.cn

View on ClinicalTrials.gov More Gastric (Stomach) Cancer trials