Microbial Community Characteristics in Intestinal Mucosal Tissue of Patients With CD (NCT06895772) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Microbial Community Characteristics in Intestinal Mucosal Tissue of Patients With CD
China50 participantsStarted 2024-11-01
Plain-language summary
The characteristics of the intestinal microbiota in Crohn's disease and their relationship with disease pathogenesis have not yet been fully elucidated. Therefore, this study aims to analyze the microbial community characteristics in the intestinal mucosal tissue of Crohn's disease patients and fill this knowledge gap. Additionally, this research holds significant importance for understanding the etiology of Crohn's disease and predicting treatment outcomes.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with Crohn's disease undergoing endoscopic examination
* Healthy individuals with no symptoms undergoing colonoscopy without any lesions detected
* Patients undergoing small intestinal endoscopy due to symptoms but with negative examination results.
* Age between 18 and 80 years.
* Patients or authorized family members sign the relevant informed consent forms.
Exclusion Criteria:
* Patients with concurrent digestive system diseases that may affect the study results, including tumors, infections, or other autoimmune diseases.
* Patients with concurrent non-digestive system diseases that may affect the study results, including tumors, infections, or autoimmune diseases.
* Patients who have taken probiotics or antibiotics within the past week.
* Patients with psychiatric disorders or other conditions that prevent them from cooperating with the study.
* Patients participating in other clinical trials that may interfere with the results of this study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The characteristics of the intestinal microbiota in Crohn's disease