CompletedNot Applicable

Zinc Stents for the Treatment of Gingivitis

Turkey (Türkiye)42 participantsStarted 2023-10-01

Plain-language summary

Background This study investigates the effects of zinc-containing stents on gingival inflammation, bleeding, and plaque regrowth in gingivitis patients. Methods A randomized, double-blind, placebo-controlled study was conducted at Çukurova University, enrolling 42 systemically healthy gingivitis patients aged 18-30. Participants were assigned to either a test group (zinc-containing stents) or a control group (placebo stents) and instructed to wear their stents for at least 12 hours daily for four weeks. Clinical measurements, including Gingival Index (GI), Plaque Index (PI), and Bleeding on Probing (BOP), were assessed at baseline, and at the 2nd, 4th, and 8th weeks. Statistical analysis was performed using IBM SPSS and RStudio.

Who can participate

Age range18 Years – 30 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Presence of plaque-induced gingivitis \[bleeding on gentle probing at \>30% of sites examined and a gingival index (GI) of at least 1 at \>60% of sites examined\], * Plaque index (PI) of ≥ 2 according to the modified Quigley\&Hein index, * 18-30 years old, * At least 20 natural teeth, * Systemically healthy. Exclusion Criteria: * Pocket probing depth (PPD) of ≥4 mm, * Interdental clinical attachment loss (CAL) detectable at ≥2 nonadjacent teeth or displaying buccal/oral CAL ≥3 mm coupled with PD ≥3 mm * Subjects with a history of allergies to Zinc, * The presence of hematologic disorders or any other systemic illness, * Pregnancy and breastfeeding, * Current orthodontic treatment, * History of periodontal therapy, * Use of antibiotics or anti-inflammatory medication within the preceding 6 months, * Smoking.

What they're measuring

Gingival index

Timeframe: Baseline, 2nd week, 4th week, 8th week

Trial details

NCT IDNCT06888440

SponsorCukurova University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-04-01