Active — Not RecruitingNot Applicable

Comparison of MiSight 1-Day and Acuvue Oasys for Presbyopia in Myopic Children

Australia72 participantsStarted 2021-02-11

Plain-language summary

This study will compare the effects on myopia progression over the course of one year for eyes wearing MiSight 1 Day contact lenses compared to ACUVUE OASYS for PRESBYOPIA contact lenses.

Who can participate

Age range6 Years – 12 Years

SexALL

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Inclusion criteria

✓. Aged 6-12 years (inclusive)
✓. Is willing to wear soft contact lenses daily
✓. Spherical equivalent myopic refractive error between -0.50 to -5.00 D in each eye and astigmatism \< 1.00 D
✓. Best corrected logMAR visual acuity of 0.1 or better in both eyes
✓. Good ocular and general health
✓. No previous use of myopia control interventions for more than 1 month or within the last 30 days
✓. Competent enough in English to be able to fully understand the participant information and consent form

Exclusion criteria

✕. Strabismus at distance or near, amblyopia or significant anisometropia (\>1D)
✕. Systemic or ocular conditions that may affect contact lens use (e.g., allergy) or that may affect refractive development (e.g., ptosis)
✕. Previous history of ocular surgery, trauma, or chronic ocular disease
✕. Contraindications to contact lens use
✕. Ocular or systemic medication use which may interfere or interact with contact lens wear or ocular development
✕. Plans to migrate or move during the study
✕. Child, parents or guardians not willing to comply with treatment and/or follow-up schedule

What they're measuring

Axial length progression

Timeframe: 1 month, 6 months and 12-months post intervention commencement. Initial protocol also included 3-month time point, but the 3-month visit was updated to a telehealth consultation due to COVID-19 restrictions. Updated after 9 participants.

Cycloplegic autorefraction

Trial details

NCT IDNCT06887920

SponsorPauline Kang

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12

View on ClinicalTrials.gov More Myopia Progressing trials