Prediction of LVAR and MACE in STEMI Though Plasma Multiomics Analysis (NCT06885619) | Clinical Trial Compass
RecruitingNot Applicable
Prediction of LVAR and MACE in STEMI Though Plasma Multiomics Analysis
China1,000 participantsStarted 2025-05-01
Plain-language summary
To identify plasma multi-omics biomarkers that predict left ventricular adverse remodeling (LVAR) and major adverse cardiovascular events (MACE) in patients with acute ST-segment elevation myocardial infarction, and to investigate the molecular pathways linked to LVAR and MACE.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age ≥18 years and ≤80 years.
. Definite diagnosis of STEMI according to ESC/ACC guidelines:
. Reperfusion therapy: Symptom onset to first medical contact ≤12 hours, and successful primary PCI (culprit vessel opened, post-procedure TIMI flow grade 3).
. First STEMI (no prior history of myocardial infarction).
. Left ventricular ejection fraction (by echocardiography within 24-48 hours after admission) ≥35%.
. Informed consent: Signed informed consent obtained, with willingness to undergo serial blood sampling and echocardiographic follow-up.
Exclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is studying plasma multi-omics and immunomics to predict bad heart outcomes after a STEMI — can you explain what those types of blood analysis actually measure, and whether the results from this study could eventually change how my own follow-up care is managed?
2Since this trial is listed as 'Phase NA,' it sounds more like an observational or biomarker study rather than a treatment trial — does that mean participating wouldn't change what treatments I receive, and are there any risks involved in giving blood samples for this kind of research?
3The study is looking at left ventricular remodeling after a STEMI, which is when the heart muscle changes shape after a heart attack — how likely is that to happen in my case, and how is my care team already monitoring me for it outside of this trial?
4This trial is focused on predicting major adverse cardiovascular events — if I don't join, are there other established tests or monitoring approaches my care team would use to assess my risk of a future heart event after my STEMI?
5Given that I'm recovering from a STEMI, would participating in this study require extra clinic visits or procedures beyond my standard recovery care, and is that realistic given where I am in my recovery right now?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.