WithdrawnPhase 2

Reusable Face Masks to Reduce Risk of Viral Respiratory Infections and Asthma Exacerbations

Stopped: Diminished minimum sample size needed to detect any effect of the intervention due to TwiCs study design, control arm participants were already recruited to the parent study (COVIDENCE UK).

United Kingdom0Started 2025-03-27

Plain-language summary

REMASK trial is a Trial within Cohort study (TwiCs), nested within the COVIDENCE UK longitudinal study. It has been designed to determine whether the offer of a free reusable, elastomeric face mask to adults with asthma and other members of their household reduces risk of RT-PCR confirmed viral respiratory infections and asthma exacerbations.

Who can participate

Age range

16 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Eligibility criteria, participants with asthma ('index participants'): Inclusion Criteria: * Aged 16 or more years * Doctor diagnosis of asthma * Current prescription for treatment of asthma * Participant in COVIDENCE UK nasal swab study Exclusion Criteria: * Regularly using any FFP-rated face mask when in an indoor public place * Currently sharing household with one or more children * Currently sharing household with one or more other COVIDENCE UK participants who have asthma * Unable to tolerate wearing face mask Eligibility criteria, household members of index participants: Inclusion criteria * Age 16 or more * Living in same household as index participant who has consented to take part in trial Exclusion criteria \- Unable to tolerate wearing face mask

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Time to first RT-PCR-proven viral respiratory infection

Timeframe: 12 months

Trial details

NCT IDNCT06885229

SponsorQueen Mary University of London

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-04-01

View on ClinicalTrials.gov More Acute Respiratory Infection trials