RecruitingPhase 3

Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.

Iraq54 participantsStarted 2025-01-05

Plain-language summary

The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah University/College of Dentistry and Wasit University /College of Dentistry. Objectives: * To assess the efficacy of anti-oxidant and anti-inflammatory resveratrol mouthwash in reducing halitosis in undergraduate students with plaque-induced gingivitis patients. * To assess the efficacy of resveratrol mouthwash in reducing p. gingivalis in undergraduate students' patients with oral malodor. * To determine the relation between p.gingivalis and clinical periodontal parameters (plaque index, gingival index, bleeding on probing) among undergraduate students with plaque-induced gingivitis and halitosis.

Who can participate

Age range

20 Years – 24 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Organoleptic tongue of scores \> 2 using (0-5scale) (Rosenberg and McCulloch, 1992) * Male and female undergraduate dental students without chemical plaque control measures for at least one weak * Male and female students with halitosis due to gingivitis * The age of students ranges from 20 to 23 years. * No periodontal treatment for at least one month * No systemic disease * No tobacco smoking * The patients must have at least 20 teeth Exclusion Criteria: * Smokers and alcoholics * Patient with periodontitis or pocket depth \> 6mm * Patient with orthodontics appliance * Open carious lesions, pericoronitis, dry socket, and fistula. * Patients with systemic disease and condition * taking medication in the last two weeks * Take garlic, onion, or licorice in the last 24 hours * using oral hygiene products in the last 24 hours * pregnant women * sinusitis, tonsilitis, and upper respiratory tract infection

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

change in oral halitosis (oral malodor)

Timeframe: Baseline (Day 0) and after 7 days

change in clinical periodontal parameters ( gingival index)

Timeframe: Baseline (Day 0) and after 7 days

change in clinical periodontal parameters (plaque index)

Timeframe: Baseline (Day 0) and after 7 days

change in clinical periodontal parameters (bleeding on probing)

Timeframe: Baseline (Day 0) and after 7 days

change in p.gingivalis level

Timeframe: Baseline (Day 0) and after 7 days

Trial details

NCT IDNCT06882564

SponsorAl-Mustansiriyah University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-04-01

Contact for this trial

NOOR AA TAHER, B.D.S

07803432060 Ext. +964 noor-aliabed@uomustansiriyah.edu.iq

View on ClinicalTrials.gov More Halitosis trials

Plain-language summary

Who can participate

Age range

20 Years – 24 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

change in oral halitosis (oral malodor)

Timeframe: Baseline (Day 0) and after 7 days

change in clinical periodontal parameters ( gingival index)

Timeframe: Baseline (Day 0) and after 7 days

change in clinical periodontal parameters (plaque index)

Timeframe: Baseline (Day 0) and after 7 days

change in clinical periodontal parameters (bleeding on probing)

Timeframe: Baseline (Day 0) and after 7 days

change in p.gingivalis level

Timeframe: Baseline (Day 0) and after 7 days