Vaginal Probiotics During Pregnancy After Premature Rupture of Membranes

Inclusion Criteria: * Groups A and B: Women ≥ 18 years of age, mono-fetal pregnancy, hospitalized for PPROM between 32 0/7 d and 36 0/7 d weeks of ammenorhea with LP \< 7 days in one of the participating centers, with expectant management, who have consented to participate, agree to collect samples and speak French or English Group C: Women ≥ 18 years, mono-fetal pregnancy, expected delivery in one of the participating centers and speaking French or English Exclusion Criteria: * Groups A and B: * Presence of active labor, * Situations contraindicating expectant management (e.g. infection), * Significant malformation, chromosomal abnormality or fetal death, * Signs of fetal distress, * vaginal probiotics intake 15 days before study entry. For Group A only: * Allergies to soy and/or milk; * Weakened immune system (e.g. AIDS, prolonged treatment with corticosteroids), * Not to have been treated with the following antibiotics during pregnancy: nalidixic acid (Negram) and/or cefoxitin (Mefoxin) and/or sulfamethoxazole (Bactrim). Group C: * History of obstetric complications (prematurity \<37 weeks, diagnosed pre-eclampsia, gestational diabetes treated with insulin), * Known obstetrical or fetal complications of the current pregnancy, such as threat of preterm delivery (premature rupture of membranes or preterm labor), chorioamnionitis, placenta previa, active vaginal bleeding, cervical cerclage, fetal distress or malformation, corticosteroid therapy, * Risk factors…