RecruitingNot Applicable

Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's Disease

China60 participantsStarted 2024-08-01

Plain-language summary

This study evaluates the clinical effect and safety of acupuncture combined with moxibustion in improving motor symptoms of early-stage Parkinson's Disease (PD) patients, by assessing the changes in UPDRS scores. It also explores objective factors affecting the acupuncture effect and investigates the functional MRI mechanisms of acupuncture in PD treatment.

Who can participate

Age range30 Years – 80 Years

SexALL

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Exclusion criteria

✕. Diagnosed with Parkinson-plus syndromes or other secondary parkinsonism.
✕. Prior history of deep brain stimulation (DBS) surgery.
✕. Severe cerebrovascular disease, brain trauma, or history of craniotomy.
✕. Severe dementia or psychiatric disorders that prevent cooperation with study procedures.
✕. Severe coagulation disorders.
✕. Presence of severe systemic organ dysfunction (cardiac, pulmonary, hepatic, renal, endocrine, or metabolic disorders).
✕. Pregnant or breastfeeding women.
✕. History of allergic reaction to acupuncture or moxibustion.

What they're measuring

The score change from baseline in the MDS-UPDRS part III after 8-week treatment

Timeframe: evaluation time points: baseline, week 8.

Trial details

NCT IDNCT06874803

SponsorJiani Wu

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-31

Contact for this trial

Yu Liu, MD

8572650199 yliu133@mgh.harvard.edu

View on ClinicalTrials.gov More Parkinson's Disease (PD) trials