The Significance and Indications of Surgery for Synchronous Liver Metastatic Pancreatic Cancer

Inclusion Criteria: * Age 18-75 years old * Pancreatic cancer was diagnosed as pancreatic ductal adenocarcinoma by biopsy of primary/metastases * Physical Condition Score (ECOG)0-1 * Simultaneous/prior discovery of liver metastases and primary lesions was defined as simultaneous liver metastases * Enhanced CT/MRI can detect liver metastases (if the diseases not detected by enhanced CT/MRI during screening are not included in the number calculation) * The patient's liver, kidney and bone marrow function is good Exclusion Criteria: * The primary lesions of pancreatic cancer are acinar cell carcinoma of pancreas, neuroendocrine carcinoma of pancreas and other pathological types * there are other metastases outside the liver * Had other malignant tumors within 5 years * History of central nervous system disease, mental illness, unstable angina pectoris, congestive heart failure, severe arrhythmia and other serious diseases * Active or chronic hepatitis B/C virus infection * Allergy to iodine, unable to perform enhanced imaging * Previous anti-tumor therapy for pancreatic cancer (surgery/ radiotherapy/ chemotherapy/ ablation/ targeted therapy/ immunotherapy)