Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism (NCT06873048) | Clinical Trial Compass
CompletedNot Applicable
Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism
Canada32 participantsStarted 2025-02-26
Plain-language summary
The primary objective of the study is to evaluate and compare the performance of two soft contact lens.
Who can participate
Age range
17 Years – 42 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. At least 17 years and no more than 42 years of age.
. Have read and signed the study consent form.
. Are willing and able to follow instructions and maintain the appointment schedule.
. Are habitual wearer of spherical soft contact lenses (not toric or multifocal design), any brand and any replacement frequency.
. Are willing to wear the study contact lenses for 6 days a week while in this study and on three days (day 1, Day 7 and Day 13) for at least 12 hours.
. Are willing to provide a contact email and telephone number and to use a device that allows them to respond to a short online questionnaire every 3 hours on days 1, 7 and 13 of each lens arm, while wearing one of the 2 study lenses.
. Are non-presbyopic i.e. no requirement for a reading addition for routine daily tasks (self report).
. Have astigmatism of either -0.50, -0.75, -1.00 or -1.25 DC in each eye by subjective sphero-cylindrical refraction.
Exclusion criteria
. Are participating in any concurrent clinical interventional study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Contact Lens Comfort
Timeframe: Day 1 (day after dispense), Day 7 and Day 13 at 12 hours contact lens wear
. Have worn rigid contact lenses in the last 3 months.
. Have worn soft toric contact lenses in the past 3 months.
. Have any known active ocular disease or allergies and/or infection.
. Have clinically significant biomicroscopy findings or have an ocular condition that contraindicate contact lens wear.
. Have a systemic condition that in the opinion of the investigator may affect a study outcome variable or contraindicate wearing soft contact lenses.
. Are using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable or contraindicate wearing soft contact lenses.
. Have known sensitivity to the diagnostic sodium fluorescein to be used in the study.