Not Yet RecruitingNot Applicable

CRacking the HEterogeneity of Social Outcome Through Neuropsychophysiological Profiles

100 participantsStarted 2025-05-01

Plain-language summary

CRHESO aims at overcoming the considerable burden of mental disorders, which affects both psychosocial well-being and societal welfare, through a multidisciplinary and integrated approach to explore and remediate dimensions affecting social outcome.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 18 and 65 years * Diagnosis of Schizophrenia according to DSM V criteria * Ability to provide informed consent Exclusion Criteria: * Intellectual disability * Neurological disorder

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Analysis of the difference in neurocognitive data between patients and controls

Timeframe: through study completion, an average of 2.5 years

Analysis of the difference in sociocognitive data between patients and controls

Timeframe: through study completion, an average of 2.5 years

Analysis of the difference in pragmatic data between patients and controls

Timeframe: through study completion, an average of 2.5 years

Analysis of the difference in language data between patients and controls

Timeframe: through study completion, an average of 2.5 years

Tracking down the difficulties in metaphor comprehension via task during electrophysiological recording

Timeframe: through study completion, an average of 2.5 years

Analysis of the impact of neuropsychological and electrophysiological measures on quality of life

Timeframe: through study completion, an average of 2.5 years

Trial details

NCT IDNCT06869616

SponsorIRCCS San Raffaele

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-11-01

Contact for this trial

Giulia Agostoni, PsyD, PhD

00393938584311 agostoni.giulia@hsr.it

View on ClinicalTrials.gov More Schizophenia Disorder trials