RecruitingNot Applicable

Syncytiotrophoblast-derived Extracellular Vesicles in Placenta Previa and Accreta Spectrum

Italy70 participantsStarted 2023-07-10

Plain-language summary

The main goal of this case-control study is to quantify the levels of circulating syncytiotrophoblast-derived extracellular vesicles (STBEVs) in maternal blood in a population of women with placenta previa and placenta accreta spectrum.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pregnant women with diagnosis of placenta previa and accreta spectrum (cases) * Healthy pregnant women * \> 18 years Exclusion Criteria: * \< 18 years * Twin pregnancies * Chronic Infections * Cancers * Unable to give the written consent

What they're measuring

Concentration of circulating EVs from blood

Timeframe: 9 months (three trimester of pregnancy)

Proteomics analysis of circulating EVs

Timeframe: 9 months (three trimester of pregnancy)

Trial details

NCT IDNCT06867874

SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-03-01

Contact for this trial

Chiara Tersigni

+39 3206557088 chiara.tersigni@policlinicogemelli.it

View on ClinicalTrials.gov More Placenta Previa trials