CompletedNot Applicable

How Seasons Affect Kidney Health in Post-Menopausal Females

United States18 participantsStarted 2025-01-03

Plain-language summary

The investigators are assessing how seasonal changes affect kidney function biomarkers in post-menopausal women, an understudied group. While heat stress can reduce kidney function, previous research has not accounted for physical activity, diet, hydration, or sun exposure.

Who can participate

Age range55 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female aged ≥55 years old * Self Reported as at least one year post-menopause * Live in Tallahassee, Florida, or the surrounding area Exclusion Criteria: * Have a BMI of ≥30 kg/m2 * Systolic blood pressure of ≥140 and/or diastolic blood pressure ≥90 mmHg * Self Reported Current or recent (regular use within the past six months) use of a diuretic medication * Self Reported: Uncontrolled cardiovascular, respiratory, neurological, renal, liver, or metabolic health condition * Current or recent (regular use within the past six months) use of tobacco, nicotine, nonsteroidal anti-inflammatory products * No regular (≥once per week) purposeful heat exposure (e.g., sauna, spa, etc.)

What they're measuring

Plasma neutrophil gelatinase-associated lipocalin (NGAL)

Timeframe: Visit 1 (0 months) and Visit 2 (7 months)

Urinary neutrophil gelatinase-associated lipocalin (NGAL)

Timeframe: Visit 1 (0 months) and Visit 2 (7 months)

Insulin-like growth factor-binding protein 7 (IGFBP7)*Tissue inhibitor of metalloproteinase-2 (TIMP-2)

Timeframe: Visit 1 (0 months) and Visit 2 (7 months)

Trial details

NCT IDNCT06866743

SponsorFlorida State University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-09-03

View on ClinicalTrials.gov More Postmenopausal trials