By InvitationNot Applicable

Evaluation of Endoscopic Treatment Effect Based on HVPG

China50 participantsStarted 2024-11-01

Plain-language summary

This study aims to evaluate the endoscopic treatment effect and related influencing factors of patients with esophageal and gastric varices based on HVPG. By enrolling and collecting patients with esophageal and gastric varices at different stages of liver cirrhosis, the changes in portal pressure before and during endoscopic treatment were detected. The endoscopic treatment effect of different patients was evaluated by combining the changes in HVPG and the condition of varicose veins, the effects of different endoscopic treatment methods on HVPG were analyzed, and the correlation between HVPG changes and endoscopic efficacy was explored.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. Age range: 18-80 years old;
✓. Patients with confirmed cirrhosis through clinical, imaging or pathological evidence, with causes including viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, etc.;
✓. Patients with esophageal and gastric varices confirmed by endoscopic examination and varicose vein bleeding in the past;
✓. Endoscopic treatment (such as band ligation, sclerotherapy or colloid injection) is an appropriate secondary prevention method;

What they're measuring

HVPG

Timeframe: Regular endoscopic treatment, with HVPG testing repeated approximately every 6-12 months

Trial details

NCT IDNCT06863519

SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-11-01

View on ClinicalTrials.gov More Esophageal and Gastric Varices trials