RecruitingNot Applicable

Cochlear Implant Speech in Noise Processing

United States150 participantsStarted 2024-11-14

Plain-language summary

The study will help us in understanding the neural mechanisms by which listeners with a cochlear implant detect speech in noisy environments.

Who can participate

Age range

18 Years – 99 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Between 18 and 99 years of age.
. Have a cochlear implant activated for more than one year.
. Eligible for research under the Iowa Cochlear Implant Project VIII.
. Ability to understand and willingness to sign a written informed consent document.
. Severe hearing loss after age 16.
. Between 18 and 99 years of age.
. Have age typical hearing.
. Eligible for research under the Iowa Cochlear Implant Project VIII.

Exclusion criteria

. Medical history includes seizure disorder, head injury, neurologic, metabolic, cardiovascular disease, or previous cerebrovascular event (unless approved by PI).
. Female self-reporting pregnancy. A urine pregnancy test will be performed prior to injection of the radiopharmaceutical.
. Currently taking medications which may affect cerebral blood flow (e.g., papaverine, ginkgo biloba, acetazolamide).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

To identify the cortical bases for speech-in-noise understanding in cochlear implant users

Timeframe: Basline Visit

Trial details

NCT IDNCT06860152

SponsorCraig D. Workman, PhD

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-03-31

Contact for this trial

Craig D Workman, PhD

(319) 384-5468 craig-workman@uiowa.edu

View on ClinicalTrials.gov More Hearing Loss, Adult-Onset trials