Not Yet RecruitingNot Applicable

Magnetic Resonance Imaging in Patients with Trigeminal Neuralgia

120 participantsStarted 2025-03-10

Plain-language summary

This study intends to use MRI technology to analyze the dynamic changes and microstructure changes of the brain network in patients with trigeminal neuralgia, evaluate the blood-brain barrier and water exchange rate, and further analyze their correlation with clinical indicators, so as to explore the changes in brain structural plasticity and potential neural mechanisms

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The diagnosis was TN according to the ICHD. * Patients requiring surgical treatment due to ineffective or intolerant treatment with carbamazepine or oxasepine before operation; * First surgical treatment; * Right-handed dominant; * There was no significant loss of sensation Exclusion Criteria: * Secondary TN; * Associated with other types of chronic pain or neuropsychiatric disorders; * History of head trauma or stroke or cerebrovascular ischemia; * History of microvascular decompression or other treatments (gamma knife radiosurgery, etc.); * Unable to cooperate independently; * Contraindications, such as uncontrolled infection, coagulopathy, etc.; * MRIcontraindications (e.g., pacemaker, claustrophobia, etc.)

What they're measuring

Scanning sequence of magnetic resonance imaging (MRI)

Timeframe: Preoperative routine MRI examination

Trial details

NCT IDNCT06853119

SponsorTongji Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-01-01

View on ClinicalTrials.gov More Trigeminal Neuralgia (TN) trials