The Role of Root Canal Treatment in Alleviating Endodontic Pain-Induced Asymmetry and Restoring M… (NCT06853028) | Clinical Trial Compass
CompletedNot Applicable
The Role of Root Canal Treatment in Alleviating Endodontic Pain-Induced Asymmetry and Restoring Muscle Balance
Turkey (Türkiye)20 participantsStarted 2023-09-01
Plain-language summary
The study hypothesizes that masticatory laterality caused by acute apical periodontitis pain result in muscle asymmetry. Furthermore, it posits that successful root canal treatment, by restoring normal bilateral chewing function, will reduce this asymmetry, as evidenced by ultrasonographic measurements of the masseter and anterior temporal muscles.The main question it aims to answer is:
Can bilateral chewing function be restored after root canal treatment procedures in patients with masticatory laterality due to painful teeth due to acute apical periodontitis?
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria
* Patients with masticatory laterality due to tooth pain for at least 30 days
* First and second maxillary or mandibular molars with acute apical periodontitis due to deep caries
* Teeth with moderate or severe pain according to the VAS (no pain (0 mm), mild pain (1-3 mm), moderate pain (4-6 mm), and severe pain (7-10 mm))
* Teeth that responded positively to percussion test
* Teeth without periapical pathosis were included in the study. Exclusion Criteria
* Systemic conditions affecting muscle structure or function, such as neuromuscular or endocrine disorders.
* Non-endodontic odontogenic pain.
* Prior endodontic treatment of the relevant tooth within the last 30 days.
* History of trauma or surgery to the head, face, or teeth within the last six months.
* Severe communication disorders or psychological issues.
* Inability to complete treatment in a single visit due to exudation or bleeding
* Patients with masticatory laterality due to missing tooth on any side of the dental arch
* Patients who have painful teeth in opposite sides of the dental arch
* TMD patients were excluded from the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Ultrasonography
Timeframe: immediately before root canal treatment, 1 week after and 3 months after the treatment