This study aims to establish and optimize the trophoblast cell surface antigen 2 (Trop2)-targeted immuno-positron emission tomography/computed tomography (immunoPET/CT) imaging method and its physiological and pathological distribution characteristics, based on which the diagnostic efficacy of the above imaging agents in solid tumors (including uroepithelial cancer, bladder cancer, prostate cancer, lung cancer, nasopharyngeal cancer, liver cancer, cholangiocarcinoma, ovarian cancer, cervical cancer, endometrial cancer, thyroid cancer, head and neck cancer) will be evaluated.
Age range
18 Years – 75 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Biodistribution-Standardized uptake value (SUV) of normal tissues and organs.
Timeframe: 1 day from injection of the tracers
SUV of tumors
Timeframe: 1 day from injection of the tracers
Radiation dosimetry of tissues/organs
Timeframe: 1 day from injection of the tracers
Radiation dosimetry of tumors
Timeframe: 1 day from injection of the tracers
Radiation dosimetry of whole-body
Timeframe: 1 day from injection of the tracers
Diagnostic sensitivity
Timeframe: 30 days
Diagnostic specificity
Timeframe: 30 days
Accuracy
Timeframe: 30 days
Positive Predictive Value (PPV)
Timeframe: 30 days
Negative Predictive Value (NPV)
Timeframe: 30 days