CompletedNot Applicable

Validation of New Type Radiopaque Marker in The Evaluation of Colonic Transit Time

Thailand20 participantsStarted 2025-03-30

Plain-language summary

The goal of this clinical trial is to learn if the local made colonic transit capsule can be use to diagnose slow transit constipation. The main questions it aims to answer are: * Does the local made colonic transit capsule correlate with the standard colonic capsule in the diagnosis of slow transit constipation? * Does the number of remained radiopaque marker similar between the two test after five days of ingestion? Researchers will compare the local made colonic capsule with the standard Sitzmark colonic capsule to see the correlation. Participants will: * Take both local made colonic capsule and Sitzmark colonic capsule at the same time. * Obtain abdominal x-ray 5 days after capsule ingestion. * Keep a diary of their symptoms and medication used during investigation.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy volunteers with normal bowel habit not meet the criteria for functional constipation and irritable bowel syndrome with constipation according to Rome IV criteria * Participants with constipation according to Rome IV criteria Exclusion Criteria: * Previous abdominal surgery * Participants at risk for intestinal obstruction such as endometriosis, history of intra-abdominal infection * Receive medication which affect colonic transit such as opioids * Pregnancy

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Correlation in the number of retained radiopaque markers from abdominal x-ray

Timeframe: 5 days after intervention

Correlation in the diagnosis of slow transit constipation with radiopaque marker method

Timeframe: 5 days after intervention

Trial details

NCT IDNCT06850415

SponsorMahidol University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-30

View on ClinicalTrials.gov More Slow Transit Constipation trials