Comparison of Oxcarbazepine Versus Carbamazepine in the Management of Trigeminal Neuralgia (NCT06849219) | Clinical Trial Compass
Active — Not RecruitingPhase 4
Comparison of Oxcarbazepine Versus Carbamazepine in the Management of Trigeminal Neuralgia
Pakistan122 participantsStarted 2024-09-21
Plain-language summary
Trigeminal neuralgia is a debilitating neurological condition, affecting quality of life in most affected patients. Carbamazepine has traditionally been used for the management of this condition, but it has a moderate effectiveness and a poor side-effect profile. Oxcarbazepine is more tolerable, and has a more favorable side-effect profile. This study aims to compare the effectiveness of oxcarbazepine and carbamazepine in the management of this condition, for improved prescription practices in the future.
Who can participate
Age range
25 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients of either gender (male or female)
* Patients of age 25-80 years
* Patients presenting with trigeminal neuralgia of any frequency and severity (according to operational definition) for six months
* Patients not already receiving carbamazepine or oxcarbazepine for the management of trigeminal neuralgia
Exclusion Criteria:
* Patients who have undergone any surgical procedure for the treatment of trigeminal neuralgia
* Patients with renal and hepatic issue such as chronic renal failure and chronic liver disease
* Patients not already receiving carbamazepine or oxcarbazepine for the management of trigeminal neuralgia
* Patients with seizures
* Patients who are intolerant to and allergic to both treatment drugs (oxcarbazepine and carbamazepine)
* Pregnant and Iactating mothers
* Patients who are not willing to participate in the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.