This study evaluates the outcomes of Holmium laser enucleation of the prostate (HoLEP) during both the learning and expert phases compared to transurethral resection of the prostate (TURP) in managing benign prostatic obstruction (BPO)-related lower urinary tract symptoms (LUTS). A prospective analysis of 200 men was conducted, dividing them into three groups: TURP (n=100), HoLEP during the learning curve (n=50), and HoLEP post-learning curve (n=50). Key outcomes assessed included the learning curve, perioperative safety, efficacy, functional recovery (IPSS, QoL, Qmax, PVR), surgical efficiency, and complication rates.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Surgical efficiency
Timeframe: Perioperative/Periprocedural
Preoperative International Prostate Symptom Score (IPSS)
Timeframe: Baseline
Postoperative International Prostate Symptom Score (IPSS)
Timeframe: 6 months
Preoperative Quality of Life (QoL)
Timeframe: Baseline
Postoperative Quality of Life (QoL)
Timeframe: 6 months
Preoperative Maximum urinary flow rate (Qmax) on uroflowmetry
Timeframe: Baseline
PostoperativeMaximum urinary flow rate (Qmax) on uroflowmetry
Timeframe: 6 months
Operation duration
Timeframe: Perioperative/Periprocedural
Learning curve
Timeframe: through study completion, an average of 6 months