The Influence of Acute Continuous Exercise and Adiposity on Appetite Hormones and Neural Correlates of Visual Food Cues

Inclusion Criteria: * Body mass index (BMI) between 18.5 - 24.9 kg/m2 and a waist circumference of ≤ 88 cm for women, and ≤ 102 cm for men or a BMI between 25 - 40 kg/m2 and a waist circumference of \> 88 cm for women, and \> 102 cm for men. BMI and waist circumference thresholds vary amongst ethnicities. People with a South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family background are prone to central adiposity and their cardiometabolic risk occurs at a lower BMI. Therefore, the following BMI and waist circumference thresholds will be applied for people of South Asian, other Asian, Black African and African-Caribbean ethnicity: (1) BMI 18.5 kg/m2 to 23 kg/m2 and waist circumference of \< 90 cm for men and \< 80 cm for women; (2) BMI 23.1 kg/m2 to 40 kg/m2 and waist circumference of ≥ 90 cm for men and ≥ 80 cm for women. * Normally consumes three meals a day * Able to walk continuously for 1 hour on a treadmill * Weight stable for 3 months (\< 3kg change in weight) * Regular menstrual cycle for the last 6 months (people taking the combined contraceptive pill are eligible for the study) * Able to undergo a 45-minute MRI scan Exclusion Criteria: * Smokers (vaping is considered smoking in this study) * Known medical conditions (e.g. diabetes, heart condition) * Taking any medication which may affect the study outcomes (e.g. liraglutide, semaglutide, insulin, steroids, anti-psychotics) * Clinically diagnosed eating disorder * Previous ba…