Active — Not RecruitingPhase 1/2

A Chatbot To Support Substance Use Recovery

United States55 participantsStarted 2025-03-07

Plain-language summary

The goal of this clinical trial is to learn if/how an AI chatbot can support patients who in recovery for substance use, specifically those who are receiving medication for opioid use disorder. Can the chatbot help lower drug use? Can the chatbot help improve clinical appointment adherence? Can the chatbot help patients build self-efficacy in leading their own recovery journey? Will the chatbot help reduce workload burden for primary care teams? Can the chatbot serve as a safe, useful and engaging tool to support patients? Researchers will investigate the effects of using a chatbot to support follow-up care for patients in opioid use recovery. Participants will: * Receive access to a chatbot for 12 weeks that they can use to prepare for upcoming clinical appointments, find community resources, learn about urge-surfing and wellness techniques, and query for assistance with other recovery-related information and tasks * Complete surveys and provide user feedback

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-65 years old * Comfortable with reading, understanding, and communicating in English * Receiving medication treatment for OUD at MGH? * Able to participate in a remote interview? * Own or have reliable access to Wi-Fi or a cellular network * Willing to use a mobile device to access the chatbot? Exclusion Criteria: * Has any cognitive, visual, or auditory impairments that may prevent the participant from using the chatbot on a mobile device? * Unstable medical condition that compromises the ability to safely participate

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in SUD severity

Timeframe: 12 weeks

Change in psychological health (Anxiety)

Timeframe: 12 weeks

Change in psychological health (Depression)

Timeframe: 12 weeks

Change in self-efficacy for managing chronic conditions (Emotions)

Timeframe: 12 weeks

Change in self-efficacy for managing chronic conditions (Social Interactions)

Timeframe: 12 weeks

Trial details

NCT IDNCT06845878

SponsorDimagi Inc.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-06-01

View on ClinicalTrials.gov More Opiate-Related Disorders trials

Plain-language summary

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in SUD severity

Timeframe: 12 weeks

Change in psychological health (Anxiety)

Timeframe: 12 weeks

Change in psychological health (Depression)

Timeframe: 12 weeks

Change in self-efficacy for managing chronic conditions (Emotions)

Timeframe: 12 weeks

Change in self-efficacy for managing chronic conditions (Social Interactions)

Timeframe: 12 weeks