RecruitingNot Applicable

MOTION Clinical Trial

United States100 participantsStarted 2025-02-13

Plain-language summary

Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated with either the MISHA Knee System or with non-surgical treatment. This is the first randomized head-to-head study comparing outcomes from subjects treated with the MISHA Knee System.

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Activity exacerbated knee pain isolated to the medial compartment and not global in nature
✓. WOMAC pain ≥ 40
✓. Failed to find relief in non-surgical treatment modalities

Exclusion criteria

✕. Large medial osteophyte(s) or considerable extruded meniscus that may interfere with the placement or function of the device
✕. Poor bone quality (e.g., bony erosion, osteopenia, osteoporosis)
✕. Ligamentous instability
✕. Active or recent knee infection
✕. Inflammatory joint disease, including sequelae of viral infections
✕. Suspected or documented allergy or hypersensitivity to cobalt, chromium, nickel or other metals
✕. History of keloid, hypertrophic or contracture scaring
✕. Propensity for restrictive scar formation or adhesions with prior procedures

What they're measuring

WOMAC Pain at 6 Months

Timeframe: 6 Months

Trial details

NCT IDNCT06843980

SponsorMoximed

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-04-30

Contact for this trial

Rose S Weinstein

(510) 887 3375 rsweinstein@moximed.com

View on ClinicalTrials.gov More Osteoarthritis, Knee trials