Not Yet RecruitingNot Applicable

The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRS

China213 participantsStarted 2025-03-14

Plain-language summary

The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is it possible that the device can treat postoperative olfactory dysfunction in patients with chronic sinusitis? Compared to the conventional device, how efficient is the modified olfactory training device for treating postoperative olfactory dysfunction in patients with chronic sinusitis?

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. A diagnosis of CRSsNP based on the European Position Paper on Rhinosinusitis and Nasal Polyps 2020 (EPOS20).
✓. The duration after endoscopic sinus surgery is 3months.
✓. Olfactory dysfunction confirmed with the Sniffin's Sticks psychophysical test (TDI score≦30.5) .
✓. Willingness to participate in this study and sign the informed consent form (ICF).

Exclusion criteria

✕. Patients with olfactory impairment due to traumatic, congenital, toxic/drug-induced causes, tumors, or post-upper respiratory infections.
✕. Lund-Mackay olfactory cleft score \> 0.
✕. Patients with severe comorbidities, such as malignant tumors.
✕. Current or planned pregnancy prior to the end of study.
✕. Patients who are unable to complete the study or are unable to comply with the requirements of the study (such as inability to tolerate olfactory function testing and treatment, memory or behavioral abnormalities, depression, smoking, heavy alcohol use, previous delinquent behavior)

What they're measuring

The Sniffin's Sticks test

Timeframe: Baseline,Month 3,Month 6,Month 12

Trial details

NCT IDNCT06837051

SponsorPeking University Third Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03-14

Contact for this trial

Dawei Wu, MD, PhD

13522503401 davidwuorl@163.com

View on ClinicalTrials.gov More Olfactory Dysfunction trials