Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults (NCT06836440) | Clinical Trial Compass
RecruitingNot Applicable
Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults
China964 participantsStarted 2025-11-10
Plain-language summary
The aim of this project is to explore whether vision correction can effectively slow cognitive decline in older adults.
The primary question it seeks to answer is: Can providing free near and/or distance vision correction glasses to older adults with refractive errors or uncorrected vision, who have normal baseline cognition and hearing, reduce the rate of cognitive decline over 36 months in a cost-effective manner? Researchers will compare the rate of cognitive decline over 36 months between older adults who receive refractive correction and those who do not.
Who can participate
Age range
60 Years – 79 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Older adults who meet all of the following criteria will be eligible to participate in this study:
* Registered as a rural resident (holding rural household registration);
* Age from 60 to 79 years at the time of enumeration;
* Resident in the household for \> = 3 months and planning to reside in the local area for the trial duration;
* Distance vision impairment (VI, presenting visual acuity \[VA\] \< 6/12 in the better-seeing eye and improving to ≥ 6/7.5 or better in either eye with spectacle correction) and/or near VI (presenting near VA \< 6/12 at 40 cm when measured binocularly and improving to ≥ 6/7.5 or better in either eye with near correction);
* Independent mobility with or without the support of a walking stick;
* Chinese version of the Mini-Mental State Examination (C-MMSE) score above the following cut-offs (out of 30): \>17 for illiterate participants, \>20 for those with primary school education, \>22 for those with junior high school education, and \>23 for those with high school education or above.
* Willingness to participate, to be randomized to either study group, and to adhere to the protocol
Exclusion Criteria:
* Presence of glaucoma or visually significant cataract, or a history of surgical treatment for these or other major ocular conditions;
* Consistent use of prescription spectacles and/or hearing aids;
* Serious medical illness likely to result in loss to follow-up. Those less severely affected by conditions …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
**Chinese version of the Global Cognitive Score Scale**
Timeframe: Each participant will undergo cognitive assessments at baseline, 12 months, 24 months, and 36 months to evaluate the impact of the intervention on cognitive decline.