CompletedPhase 4

Investigating the Bactericidal Effect of Probiotics on Chromogenic Bacteria in Children An In Vivo and In Vitro Study

Egypt9 participantsStarted 2024-11-05

Plain-language summary

To investigate the bactericidal effect of probiotics (Streptococcus salivarius M18 and Lactobacillus reuteri) on two types of bacteria (Aggregatibacter actinomycetemcomitans and Actinomyces naeslundii) causing black stains of teeth in vitro.

Who can participate

Age range6 Years – 14 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with black stains on teeth scored via modified Lobene index scores 1-3. * Medically free patients Exclusion Criteria: * Stains other than black. * Patients on antibiotic treatment or any other medication for the last 2 weeks. * Patients allergic to prophylaxis powder. * Parents refusing to participate

What they're measuring

chromogenic bacterial count before and after probiotic application

Timeframe: two weeks

Trial details

NCT IDNCT06834815

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-20

View on ClinicalTrials.gov More Black Stains trials