The goal of this observational case-control study is to evaluate the relationship between temporal bone computed tomography (CT) findings, bone mineral density (BMD), and audiological parameters in adults diagnosed with otosclerosis. The main questions it aims to answer are: Is there a correlation between temporal bone CT density values and the severity of hearing loss in otosclerosis? Do bone mineral density and serum vitamin D levels differ between otosclerosis patients and individuals without otosclerosis? Researchers will compare patients diagnosed with otosclerosis to a control group without otosclerosis to determine if CT-based density variations are associated with disease severity and systemic bone metabolism markers. Participants who have already had a temporal bone CT scan as part of their routine clinical evaluation will undergo: Bone mineral density (BMD) assessment via dual-energy X-ray absorptiometry (DEXA) Serum vitamin D level measurement Audiological testing, including pure tone audiometry and speech discrimination tests This study aims to improve the diagnostic and prognostic understanding of otosclerosis by integrating imaging, metabolic, and audiological data.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Temporal Bone CT Density Measurements
Timeframe: Baseline (Preoperative assessment)
Pure Tone Audiometry (PTA) Thresholds
Timeframe: Baseline (Preoperative assessment)
Air-Bone Gap (ABG) Measurement
Timeframe: Baseline (Preoperative assessment)
Bone Mineral Density (BMD) Scores
Timeframe: Baseline (Preoperative assessment)
Serum Vitamin D Levels
Timeframe: Baseline (Preoperative assessment)