RecruitingNot Applicable

Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars

Egypt60 participantsStarted 2024-01-01

Plain-language summary

Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries prevention. The aim of this study: This study aims to evaluate the effect of Er,Cr:YSGG subablative laser irradiation on caries resistance of occlusal fissures of permanent molars. Materials and methods: In-vivo study, a split mouth randomized controlled trial with sixty patients having two fully erupted bilateral first permanent molars (ICDAS-II score 0,1 or 2). The pits and fissures will be subjected to sub-ablative power of Er,Cr:YSGG Laser (Group 1, n=90) and will be compared with fluoride varnish application on the first permanent molars in the same arch(Group 2,n=90). DIAGNOdentTM readings and changes in ICDAS-II score will be assessed at base line and at 3,6,9 and 12 months follow-up.

Who can participate

Age range6 Years – 12 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants of age 6-12 years old * Patients ranking definitely positive or positive on Frankl behavior rating scale * Having at least two bilateral fully erupted first permanent molars with untreated non-cavitated occlusal surfaces with deep grooves, the included teeth will have International Detection and Assessment System (ICDAS-II)/ severity scores 0, 1 or 2 * Initial DIAGNOdent Score not exceeding value of 25 indicating only enamel involvement * Patients whom their parents are willing to comply with all study procedures and protocols and will be given an informed consent to participate Exclusion Criteria: * Patients with any known medical history of systemic diseases * Patients having first permanent molar with hypoplastic or hypocalcified enamel * Patients using medications that may affect the oral flora or salivary flow * Patients treated with in-office fluoride treatment within the last 3 months prior to being enrolled in the study. * Patients showing evidence of poor oral hygiene according to Silness and Löe plaque index

What they're measuring

Diagnodent scoring

Timeframe: day 0, 3 months, 6 months, 12 months

Trial details

NCT IDNCT06826456

SponsorAlexandria University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07

Contact for this trial

Hussein Ezz Eldin

+20 10 92403402 hussein.ezz@hotmail.com