This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and/or individualized exercise training intervention on blood pressure and vascular health. Furthermore the investigators want to decipher mechanisms, which contribute to vascular health by analyzing changes in metabolism and cell function in relation to vascular reaction.
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The additional effect of an anti-hypertensive treatment plus an individualizes exercise therapy on the retinal vessel diameters compared to a guideline based anti-hypertensive treatment with general lifestyle recommendations.
Timeframe: From enrollment to the end of treatment after six month.
Effect of an guideline based anti-hypertensive therapy on the retinal vessel diameters.
Timeframe: From enrollment to the end of treatment after six month.
Johannes Stegbauer, Prof. Dr.