Success of Lesion Sterilization and Tissue Repair Therapy

Inclusion Criteria: * Spontaneous pain * Pain on percussion * The presence of abnormal or pathological mobility * The presence of a sinus tract or dentoalveolar abscess * Widening of the periodontal ligament * Periradicular radiolucency * Evidence of external and/or internal resorption. Exclusion Criteria: * Who required infective endocarditis prophylaxis * Who had used antibiotics in the two weeks prior to treatment * İndividuals allergic to the medications used in the study * Teeth with pulp floor perforation * Advanced internal and/or external root resorption * Root canal obliteration * Excessive bone loss in the furcation area involving the permanent tooth follicle * Teeth with severe coronal destruction, nonrestorable.