Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion (NCT06813690) | Clinical Trial Compass
CompletedNot Applicable
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion
Switzerland48 participantsStarted 2025-03-17
Plain-language summary
The goal of this clinical trial is to learn if applying cold therapy can reduce swelling, inflammation, and pain after physical activity in adults who experience muscle soreness (Delayed Onset Muscle Soreness, or DOMS). The main questions it aims to answer are:
* Can cold therapy reduce swelling and inflammation in muscles after exercise?
* Does cold therapy reduce muscle pain and discomfort (DOMS)?
Researchers will compare participants using the Axanova Cold Hot Pearls Maxi Pack to those not receiving any cold therapy to see if the cold application improves recovery outcomes.
Participants will:
* Perform physical activity designed to induce muscle soreness.
* Use the Axanova Cold Hot Pearls Maxi Pack on the affected area as directed.
* Report their level of muscle pain, stiffness, and swelling over the following 72 hours.
The study aims to provide new insights into the effectiveness of cold therapy for muscle recovery, focusing on pain relief, reduced swelling, and improved recovery time.
Who can participate
Age range
18 Years – 30 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria
* Young, healthy adults aged between 18 and 30 years
* No surgical interventions on the musculoskeletal system in the trunk area or lower extremities
Exclusion Criteria
* Current pain conditions
* Current inflammatory conditions
* Medication use (excluding contraceptives)
* Pregnant participants
* Competitive athletes
* Children/teenagers
* Non-intact skin conditions (e.g., psoriasis)
* Known circulatory disorders
* Cold allergy (Raynaud's disease)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Reduction in Muscle Pain (DOMS)
Timeframe: 72 hours
2
Reduction in Swelling
Timeframe: 72 hours
3
Inflammatory Marker Levels
Timeframe: 72 hours
Trial details
NCT IDNCT06813690
SponsorUniversity of Applied Sciences and Arts of Southern Switzerland