Cystic fibrosis (CF) is a genetic disorder affecting exocrine glands, leading to thick, viscous secretions that damage organs such as the lungs, pancreas, and reproductive system. Respiratory failure from CF lung disease is a major cause of morbidity and mortality, with chronic inflammation and infections disrupting mucociliary clearance. This results in declining respiratory functions, muscle strength, physical inactivity, and quality of life. While some studies compare respiratory and lower extremity muscle endurance in children with CF, none have evaluated core muscle endurance. This study aims to compare respiratory muscle strength, endurance, and muscle endurance in the core and lower extremities between children with CF and healthy peers.
Who can participate
Age range6 Years – 18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria for Children with Cystic Fibrosis
* Being between the ages of 6-18,
* Being diagnosed with Cystic Fibrosis according to the American Cystic Fibrosis Association consensus guideline,
* Having a forced expiratory volume in one second (FEV1) above 40% of the predicted value
Exclusion Criteria for Children with Cystic Fibrosis
* Not being able to cooperate with the assessment methods performed in the study
* Having an orthopedic, neurological, vestibular, etc. problem that may negatively affect the assessment methods performed in the study
* Having a history of exacerbation in the last month
* Having an organ transplantation history
* Using systemic corticosteroids
Inclusion Criteria for Healthy Children
\- Being between the ages of 6-18
Exclusion Criteria for Healthy Children
* Not being able to cooperate with the assessment methods performed in the study
* Having an orthopedic, neurological, vestibular, etc. problem that may negatively affect the assessment methods performed in the study
* Having had a respiratory tract infection in the last month