Prognostic Value of PARS Classification for Locally Recurrent Rectal Cancer (NCT06808308) | Clinical Trial Compass
CompletedNot Applicable
Prognostic Value of PARS Classification for Locally Recurrent Rectal Cancer
199 participantsStarted 2011-01-01
Plain-language summary
The aim of this retrospective study was to explore the predictors of post-recurrent survival in locally recurrent rectal cancer patients undergoing salvage radical surgery. Based on the identified risk factors, investigators propose a new risk stratification to facilitate the development of strategies for surgical treatment and follow-up care.
Who can participate
Age range
20 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* (1) the primary tumor was located in the sigmoid colon or rectum, following prior radical tumor resection;
* (2) local recurrence was confirmed through CT, MRI, and serum cancer biomarker test, or endoscopic biopsy;
* (3) the recurrent site was confined to the pelvis;
* (4) the recurrent tumor underwent R0 or R1 surgical resection;
* (5) the absence of uncontrollable distant metastases at the time of salvage radical surgery.
Exclusion Criteria:
* (1) patients with unresectable tumors identified before salvage radical surgery, leading to palliative therapy;
* (2) a recurrence interval of less than three months;
* (3) incomplete baseline characteristics, including pathologic data from the initial treatment;
* (4) loss to follow-up.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
PRS
Timeframe: PRS was calculated from the date of salvage radical surgery until the date of death or until censored at the last follow-up, assessed up to 140 months.
Trial details
NCT IDNCT06808308
SponsorSixth Affiliated Hospital, Sun Yat-sen University