Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system with both inflammatory and degenerative characteristics that affects approximately 136,000 people in Italy. The highest incidence of disease onset occurs between the ages of 20 and 40, which corresponds to the most productive period of a person's life. For this reason, one of the main social consequences of MS is the reduction or abandonment of work activity, which often begins in the early stages of the disease. Vocational Rehabilitation (VR) interventions, as reported in the literature, are used to manage and reduce work-related difficulties. The goal of VR is to enable individuals who experience difficulties in performing work activities to access, find, and maintain employment. This approach is characterized by its multi-professional and multidimensional nature, involving different types of interventions carried out by various professionals in diverse settings. The overall aim of the project is to define a Vocational Rehabilitation (VR) protocol to reduce work-related challenges and promote job retention for workers with MS within the Italian healthcare and social context. The intervention will be organised into three different areas: rehabilitation, reasonable accommodation and education. Participants will receive any of the three interventions or a combination of these. The study will involve a multidisciplinary team of doctors (e.g. neurologist, physiatrist), psychologists, occupational therapists, physiotherapists, social workers, and labour law experts who will be involved according to the subject's specific needs.
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Interception
Timeframe: Up to 6 months
Acceptance
Timeframe: Up to 6 months
Adherence
Timeframe: Up to 6 months
Lost to Follow-Up
Timeframe: Up to 6 months
Canadian Occupational Performance Measure (COPM)
Timeframe: Baseline, up to 6 months
Client Satisfaction Questionnaire (CSQ)
Timeframe: Up to 6 months
Global Perceived Effect (GPE) scale
Timeframe: Up to 6 months
Barthel Index (BI)
Timeframe: Baseline, up to 6 months
Hospital Anxiety Depression scale (HADS)
Timeframe: Baseline, up to 6 months
Modified Fatigue (MFIS-21)
Timeframe: Baseline, up to 6 months
Multiple Sclerosis Neuropsychological Questionnaire for patient (MSNQ-p)
Timeframe: Baseline, up to 6 months
WHO Disability Assessment Schedule (WHODAS)
Timeframe: Baseline, up to 6 months