CompletedEarly Phase 1

Corticosteroids Prevent the Atrial Fibrillation After Cardiac Surgery

Egypt84 participantsStarted 2022-01-01

Plain-language summary

Cardiopulmonary bypass and cardiac surgery are associated with a significant systemic inflammatory response that has been suggested playing a causative role in the development of postoperative atrial fibrillation (POAF). The goal of this study is to determine the efficacy of corticosteroids prophylaxis in preventing POAF, or length of intensive care unit (ICU) or hospital stay.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Elective first time CABG or combined with valvular surgery. * Use of b-adrenergic blockade. * Normal sinus rhythm. Exclusion Criteria: * History of heart block * History of previous episodes of AF or flutter * History of peptic ulcer disease * Permanent pacemaker * Any documented or suspected supraventricular or ventricular arrhythmias * Renal insufficiency (serum creatinine \>20 mg/dL) * Uncontrolled diabetes mellitus * Systemic bacterial or mycotic infection * Urgent or emergency surgery * Patient underwent cardiac surgery without using cardiopulmonary bypass

What they're measuring

overall occurrence of postoperative AF

Timeframe: during the first 72 hours after cardiac surgery

Trial details

NCT IDNCT06802432

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07-05

View on ClinicalTrials.gov More Post Operative Arrythmia trials