Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation (NCT06801522) | Clinical Trial Compass
RecruitingPhase 2/3
Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation
Pakistan70 participantsStarted 2024-12-01
Plain-language summary
The goal of this trial is to compare efficacy of xylometazoline nasal drops and adrenaline nasal pack in participants undergoing elective oromaxillofacial surgeries.
The main question aim to answer is xylometazoline nasal drops better than adrenaline nasal packing in terms of nasal bleeding during nasotracheal intubation. Researchers are comparing 2 groups of participants.
Participants in group Xylometazoline are receiving 0.1% xylometaxoline nasal drops.
Participants in group Adrenaline are receiving adrenaline nasal packing.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ASA 1 and 2
* Age group between 18-60 years
* Mallampati score 1 and 2
* Either gender
* Participants who undergo elective oromaxillofacial surgery
Exclusion Criteria:
* Lack of consent
* Participants with anticipated difficult airway
* Participants receiving anticoagulant therapy
* History of nasal abnormality (nasal surgery, trauma, polyp, obstruction)
* History of repeated epistaxis
* History of uncontrolled hypertension, diabetes, pregnancy, and any other cardiac or cerebral events.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Nasal bleeding
Timeframe: At the time of Intubation and Extubation
Trial details
NCT IDNCT06801522
SponsorShaheed Mohtarma Benazir Bhutto Institue of Trauma
Sponsor typeOTHER
Study typeINTERVENTIONAL
Primary completion2025-03
Contact for this trial
Dr Sidra Javed Consultant Anaesthetist, MBBS, FCPS, PAIN FELLOW