Treatment of Menstrual Cycle Alterations in Adolescents

Inclusion Criteria: * adolescent women aged 14-19 years old, with at least 3 years passed after menarche, and oligomenorrhea or amenorrhea Exclusion Criteria: * Primary amenorrhea. * Hyperandrogenism due to other factors (i.e. adrenal hyperplasia or Cushing syndrome). * Hyperprolactinemia or overt hypothyroidism (TSH ≥4). * Other hormonal alterations. * Ongoing hormonal therapies, including OCPs, six months before enrollment. * Ongoing pharmacological therapies. * Ongoing use of myo-Inositol supplement or other source of myo-Inositol, or Dioscorea villosa, six months before enrollment.